Immunoglobulins are highly diverse protein sequences that are processed and presented to T-cells by B-cells and other antigen presenting cells.We examined a large dataset of immunoglobulin heavy chain variable regions (IGHV) to assess the diversity of T-cell exposed motifs (TCEM).TCEM comprise those amino acids in a MHC-bound peptide which face out

BackgroundApoptosis regulates normal development, homeostasis, immune tolerance and response to environmental stress by eliminating unwanted or diseased cells, and plays a key role in non-specific immunity of invertebrates.The exogenous pathway mediated by death receptors and death ligands is a very important pathway for cell apoptosis.Death ligand

This paper is an extension of the recent work by the authors where a simplifying assumption of no costs of entry to the religious market was set.In the present paper, the religious market is regulated in the sense that a sect in order to establish itself in a market has to bear costs of entry.In the case of one official denomination the strict sect

Predatory mites such as Neoseiulus californicus McGregor Wellbeing (Fig.1) and Phytoseiulus persimilis Athias-Henriot (Fig.2) feed on important fruits and ornamental pests such as the twospotted spider mite (Tetranychus urticae Koch), broad mite (Polyphagotarsonemus (Stenotarsonemus) latus Banks), cyclamen mite (Tarsonemus pallidus L.), and other m

Advances in the field chronobiology have potential implications for physical as well as mental health and human behavior.Several paradigm-shifting discoveries established key mechanistic principles for the biological clock.We trace the origins and key discoveries that helped to SWEET CHEEKS BABY BUM POWDER advance the field of chronobiology and a g